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Rajendra G. Mehta

IIT Research Institute
University of Illinois at Chicago

176

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Bioassay Methods Useful for Activity-Guided Isolation of Natural Product Cancer Chemopreventive Agents

2018
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Abstract 5436: Novel single-domain antibody (sdAb), SBT-100, localizes in the cytoplasm to inhibit IL-6 mediated P-STAT3 nuclear translocation in cancer cells

2018 Cancer Research
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Progression of conventional hepatic cell culture models to bioengineered HepG2 cells for evaluation of herbal bioactivities

2018 Biotechnology Letters
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Single domain antibody (SBT-100) crosses the blood brain barrier (BBB) and inhibits human glioblastoma by selectively targeting KRAS and P-STAT3.

2017 Journal of Clinical Oncology
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Abstract P6-12-13: Single domain antibody (SBT-100) inhibits growth of human HER2+ and triple negative breast cancers (TNBC) in xenografts by binding STAT3 and P-STAT3

2017 Cancer Research
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Abstract 4699: Single domain antibody (sdAb) localizes in cancer cells to inhibit signal transducer and activator of transcription 3 (STAT3) resulting in therapeutic inhibition of multiple cancers

2017 Cancer Research
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A novel single domain antibody (sdAb) SBT-100 to target intracellular STAT3 to affect growth and regression of human triple negative breast cancer (TNBC) cells.

2016 Journal of Clinical Oncology
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A novel single domain antibody (sdAb) SBT-100 targeting intracellular STAT3 to inhibit major subtypes of human breast cancer.

2016 Journal of Clinical Oncology
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LiSIs: An Online Scientific Workflow System for Virtual Screening

2015 Combinatorial Chemistry & High Throughput Screening
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Differential roles of ERα and ERβ in normal and neoplastic development in the mouse mammary gland.

2014 PLOS ONE
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