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Paul N. Bishop

University of Manchester
Central Manchester University Hospitals NHS Foundation Trust
Wellcome Trust Centre for Cell-Matrix Research

225

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6025

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Prevalence and phenotype associations of complement factor I mutations in geographic atrophy.

2021 Human Mutation
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Beyond factor H: The impact of genetic-risk variants for age-related macular degeneration on circulating factor-H-like 1 and factor-H-related protein concentrations

2021 American Journal of Human Genetics
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FHL-1 interacts with human RPE cells through the α5β1 integrin and confers protection against oxidative stress.

2021 Scientific Reports
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Intravitreal pharmacokinetic study of the anti-angiogenic glycoprotein opticin.

2020 Molecular Pharmaceutics
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Association of plasma trace element levels with neovascular age-related macular degeneration.

2020 Experimental Eye Research
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Analysis of opticin binding to collagen fibrils identifies a single binding site in the gap region and a high specificity towards thin heterotypic fibrils containing collagens II, and XI or V/XI.

2020 PLOS ONE
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Homozygous deletion of CDKN2A in malignant mesothelioma: Diagnostic utility, patient characteristics and survival in a UK mesothelioma centre.

2020 Lung Cancer
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Complement expression and immunolocalisation studies of the RPE/choroid complex provide evidence for Bruch’s membrane degradation in early AMD

2020 Investigative Ophthalmology & Visual Science
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Proteomic analysis of vitreous humor samples obtained from donors with and without age-related macular degeneration (AMD) reveal an overactivation of complement protein expression.

2020 Investigative Ophthalmology & Visual Science
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Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration

2020 Nature Communications
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Citations (31)