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Naotake Kobayashi
Naotake Kobayashi
Chemistry
In vivo
Thyrotropin-releasing hormone
Hormone
Central nervous system
8
Papers
24
Citations
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2024
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Synthesis and Evaluation of in Vivo Anti-hypothermic Effect of the N- and C-Terminus Modified Thyrotropin-Releasing Hormone Mimetic: [(4S,5S)-(5-Methyl-2-oxooxazolidine-4-yl)carbonyl]-[3-(thiazol-4-yl)-L-alanyl]-L-prolinamide.
2021
Chemical & Pharmaceutical Bulletin
Naotake Kobayashi
Norihito Sato
Katsuji Sugita
Tsuyoshi Kihara
Katsumi Koike
Tamio Sugawara
Yukio Tada
Takayoshi Yoshikawa
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Synthesis and evaluation of in vivo anti‐hypothermic effect of all stereoisomers of the thyrotropin‐releasing hormone mimetic: Rovatirelin Hydrate
2019
Journal of Peptide Science
Naotake Kobayashi
Norihito Sato
Katsuji Sugita
Kouji Takahashi
Tamio Sugawara
Yukio Tada
Takayoshi Yoshikawa
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Citations (1)
Discovery of the Orally Effective Thyrotropin-Releasing Hormone Mimetic: 1-{N-[(4S,5S)-(5-Methyl-2-oxooxazolidine-4-yl)carbonyl]-3-(thiazol-4-yl)-l-alanyl}-(2R)-2-methylpyrrolidine Trihydrate (Rovatirelin Hydrate)
2018
Naotake Kobayashi
Norihito Sato
Yuko Fujimura
Tsuyoshi Kihara
Katsuji Sugita
Kouji Takahashi
Katsumi Koike
Tamio Sugawara
Yukio Tada
Hiroshi Nakai
Takayoshi Yoshikawa
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Citations (7)
Method of producing a 4-thiazolylmethyl.
1999
Naotake Kobayashi
Masahiko Nagai
Masaaki Uenaka
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