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Isabel Freund
Isabel Freund
Heidelberg University
RNA
Biology
Cell biology
TLR7
Innate immune system
8
Papers
125
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RNA Modifications Modulate Activation of Innate Toll-Like Receptors
2019
Genes
Isabel Freund
Tatjana Eigenbrod
Mark Helm
Alexander H. Dalpke
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Citations (38)
2'-O-methylation within prokaryotic and eukaryotic tRNA inhibits innate immune activation by endosomal Toll-like receptors but does not affect recognition of whole organisms
2019
RNA
Isabel Freund
Daniel K. Buhl
Sébastien Boutin
Annika Kotter
Florian Pichot
Virginie Marchand
Tim Vierbuchen
Holger Heine
Yuri Motorin
Mark Helm
Alexander H. Dalpke
Tatjana Eigenbrod
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Citations (13)
Double methylation of tRNA-U54 to 2′-O-methylthymidine (Tm) synergistically decreases immune response by Toll-like receptor 7
2018
Nucleic Acids Research
Patrick Keller
Isabel Freund
Virginie Marchand
Guillaume Bec
Raven H. Huang
Yuri Motorin
Tatjana Eigenbrod
Alexander H. Dalpke
Mark Helm
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Citations (10)
Next‐Generation Sequencing‐Based RiboMethSeq Protocol for Analysis of tRNA 2′‐O‐Methylation
2017
Virginie Marchand
Florian Pichot
Kathrin Thüring
Lilia Ayadi
Isabel Freund
Alexander H. Dalpke
Mark Helm
Yuri Motorin
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Citations (34)
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