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Ceri M. Wiggins

Babraham Institute

15

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488

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Abstract 1927: High-throughput cell line panel drug screening in organoids and 3D systems

2019 Tumor Biology
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Abstract 2912: CRISPR-Cas9: A tool for rapid target discovery and validation

2018 Cancer Research
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Pre-clinical use of isogenic cell lines and tumours in vitro and in vivo for predictive biomarker discovery; impact of KRAS and PI3KCA mutation status on MEK inhibitor activity is model dependent.

2016 European Journal of Cancer
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Identifying synthetic lethal targets in colon cancer using CRISPR-Cas9 and siRNA screens

2016 European Journal of Cancer
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The In(del)s and Outs of CRISPR-Cas9 Screens

2016 Genetic Engineering & Biotechnology News
- Ceri M. Wiggins
- Steffen Lawo
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Refining the minimal sequence required for ERK1/2-dependent poly-ubiquitination and proteasome-dependent turnover of BIM

2010 Cellular Signalling
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Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics.

2009 FEBS Journal
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c-Cbl is not required for ERK1/2-dependent degradation of BimEL

2007 Cellular Signalling
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Opposites Attract, ERK Repels

2007
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Bim and the Pro-Survival Bcl-2 Proteins: Opposites Attract, ERK Repels

2007 Cell Cycle
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Citations (137)