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Gregory C. Leo

Monsanto

33

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633

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Can Untargeted Metabolomics Be Utilized in Drug Discovery/Development?

2017 Current Topics in Medicinal Chemistry
- Gary W. Caldwell
- Gregory C. Leo
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Suzuki−Miyaura Approach to JNJ-26076713, an Orally Active Tetrahydroquinoline-Containing αVβ3/αVβ5 Integrin Antagonist. Enantioselective Synthesis and Stereochemical Studies

2008 Journal of Organic Chemistry
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Chromatography Mass Spectrometry Based Metabonomic Analytical Methods

2006
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N-GLUCURONIDATION OF THE PLATELET-DERIVED GROWTH FACTOR RECEPTOR TYROSINE KINASE INHIBITOR 6,7-(DIMETHOXY-2,4-DIHYDROINDENO(1,2-C)PYRAZOL- 3-YL)-(3-FLUORO-PHENYL)-AMINE BY HUMAN UDP-GLUCURONOSYLTRANSFERASES

2006 Drug Metabolism and Disposition
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(6,7-Dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamines: Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitors with Broad Antiproliferative Activity against Tumor Cells

2005 Journal of Medicinal Chemistry
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Application of flow NMR to an open-access pharmaceutical environment.

2003 Analytical Chemistry
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Stereoselectivity in the rhodium(II) acetate catalysed cyclopropanations of 2-diazo-1-indanone with styrenes

2000 Tetrahedron Letters
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ARYLSULFONATE ESTERS IN SOLID PHASE ORGANIC SYNTHESIS. I. CLEAVAGE WITH AMINES, THIOLATE, AND IMIDAZOLE

1998 Tetrahedron Letters
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NMR three‐dimensional solution structure of the serine protease inhibitor cyclotheonamide A

1997 Biopolymers
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Protein structure determination using a combination of comparative modeling and NMR spectroscopy. Application to the response regulator protein, Spo0F.

1997 Journal of Medicinal Chemistry
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Citations (2)