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Palanisamy Kanakaraj

Human Genome Sciences

26

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Costimulatory Signals into Human T Cells A TNF Family Member LIGHT Transduces

2017
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Monoclonal antibody therapeutics with up to five specificities: functional enhancement through fusion of target-specific peptides.

2013 mAbs
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Simultaneous targeting of TNF and Ang2 with a novel bispecific antibody enhances efficacy in an in vivo model of arthritis.

2012 mAbs
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HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo

2005 British Journal of Cancer
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Development of a long-acting insulin analog using albumin fusion technology.

2005 Diabetes
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Pharmacokinetics and in vitro and in vivo anti-tumor response of an interleukin-2-human serum albumin fusion protein in mice

2005 Cancer Immunology, Immunotherapy
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TIP, a T-cell factor identified using high-throughput screening increases survival in a graft-versus-host disease model.

2003 Nature Biotechnology
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A TNF Family Member LIGHT Transduces Costimulatory Signals into Human T Cells

2002 Journal of Immunology
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TL1A Is a TNF-like Ligand for DR3 and TR6/DcR3 and Functions as a T Cell Costimulator

2002 Immunity
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BLyS BINDS TO B CELLS WITH HIGH AFFINITY AND INDUCES ACTIVATION OF THE TRANSCRIPTION FACTORS NF-κB AND ELF-1

2001 Cytokine
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Citations (53)