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Ludek Eyer

34

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793

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Could 5’-N and S ProTide analogues work as prodrugs of antiviral agents?

2020 Bioorganic & Medicinal Chemistry Letters
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Tick-Borne Encephalitis Virus Vaccines Contain Non-Structural Protein 1 Antigen and may Elicit NS1-Specific Antibody Responses in Vaccinated Individuals

2020 Vaccine
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An RNA-dependent RNA polymerase inhibitor for tick-borne encephalitis virus

2020 Virology
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Viral RNA-dependent RNA polymerase inhibitor 7-deaza-2'-C-methyladenosine prevents death in a mouse model of West Nile virus infection

2019 Antimicrobial Agents and Chemotherapy
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An E460D substitution in the NS5 protein of tick-borne encephalitis virus confers resistance to the inhibitor Galidesivir (BCX4430) and also attenuates the virus for mice

2019 Journal of Virology
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Tick-borne encephalitis in Europe and Russia: Review of pathogenesis, clinical features, therapy, and vaccines

2019 Antiviral Research
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An E460D substitution in the NS5 protein of tick-borne encephalitis virus confers resistance to the inhibitor Galidesivir (BCX4430) and also attenuates the virus for mice

2019 bioRxiv
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Nucleoside analogs as a rich source of antiviral agents active against arthropod-borne flaviviruses:

2018 Antiviral Chemistry & Chemotherapy
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Development and testing of a new tick-borne encephalitis virus vaccine candidate for veterinary use

2018 Vaccine
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Escape of Tick-Borne Flavivirus from 2′-C-Methylated Nucleoside Antivirals Is Mediated by a Single Conservative Mutation in NS5 That Has a Dramatic Effect on Viral Fitness

2017 Journal of Virology
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