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Genmin Lu

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ANDEXANET ALFA FOR ACUTE BLEEDING DURING TREATMENT WITH ENOXAPARIN

2021 Journal of the American College of Cardiology
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Using engineered 6-O-sulfotransferase to improve the synthesis of anticoagulant heparin.

2020 Organic and Biomolecular Chemistry
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A phase 2 PK/PD study of andexanet alfa for reversal of rivaroxaban and edoxaban anticoagulation in healthy volunteers

2020 Blood Advances
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Andexanet versus prothrombin complex concentrates: Differences in reversal of factor Xa inhibitors in in vitro thrombin generation

2020
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496: VALIDATION OF ANDEXANET ALFA REGIMEN FOR REVERSAL OF ANTICOAGULATION IN PATIENTS WITH MAJOR BLEEDING

2019 Critical Care Medicine
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Full Study Report of Andexanet Alfa for Bleeding Associated with Factor Xa Inhibitors

2019 The New England Journal of Medicine
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Effects of Andexanet Alfa on Thrombin Generation in Bleeding Associated with Factor Xa Inhibitors

2019 Blood
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Prothrombin Complex Concentrates (PCCs) Have Limited Effect on TF-Initiated Thrombin Generation in FXa Inhibitor-Anticoagulated Plasma: In Vitro Comparison between Direct Reversal By Andexanet Alfa and Work Around By PCCs

2019 Blood
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59: ANDEXANET ALFA REVERSES ANTICOAGULATION IN FACTOR XA-ASSOCIATED MAJOR BLEEDING IN ANNEXA-4 STUDY

2019 Critical Care Medicine
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Andexanet alfa effectively reverses edoxaban anticoagulation effects and associated bleeding in a rabbit acute hemorrhage model

2018 PLOS ONE
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