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Ermanno Gherardi

University of Cambridge
Laboratory of Molecular Biology
Medical Research Council

118

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10071

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A minimal hepatocyte growth factor mimic acting as a powerful agonist of the MET receptor tyrosine kinase for regeneration of epithelial tissues and organs.

2020 bioRxiv
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Generation and characterization of novel recombinant anti-hERG1 scFv antibodies for cancer molecular imaging

2018 Oncotarget
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107_A07 Fab in complex with fragment of the Met receptor

2017
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Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from the ligand binding domain

2017 Scientific Reports
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Developing Antagonists for the Met-HGF/SF Protein–Protein Interaction Using a Fragment-Based Approach

2016 Molecular Cancer Therapeutics
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Exploring the chemical space of the lysine-binding pocket of the first kringle domain of Hepatocyte Growth Factor/Scatter Factor (HGF/SF) yields a new class of inhibitors of HGF/SF-MET binding

2015 Chemical Science
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Targeting MET in cancer: rationale and progress

2012 Nature Reviews Cancer
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Non-Agonistic Bivalent Antibodies That Promote c-MET Degradation and Inhibit Tumor Growth and Others Specific for Tumor Related c-MET

2012 PLOS ONE
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Establishing Mammalian Production Cell Lines for Structural Biology by Site-Specific Recombination

2012
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Antikörper gegen hgf-rezeptor und verwendungen

2012
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