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Janet A. Houghton

St. Jude Children's Research Hospital
Cleveland Clinic

172

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Abstract 5495: GANT61-induced cell death involves inhibition of transcription and DNA licensing at GLI sites in the promoters of GLI-dependent target genes in human colon carcinoma cells

2017 Cancer Research
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Mutants of human colon adenocarcinoma, selected for thymidylate

2016
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Abstract 4689: Targeting constitutive GLI activation in colon carcinomas and cancers with oncogenic KRAS signaling

2015 Cancer Research
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Abstract 5459: Molecular mechanisms of dysregulated GLI activation in Hedgehog (HH)-dependent survival in human colon cancer.

2013 Cancer Research
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Abstract 1790A: Hedgehog signaling at the level of GLI transcriptionally regulates hTERT in human cancer cells.

2013 Cancer Research
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Hedgehog Signaling Regulates Telomerase Reverse Transcriptase in Human Cancer Cells

2013 PLOS ONE
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A unique acquired resistance mechanism to agents that target GLI (GANT61) in the Hedgehog (HH) signaling pathway

2013 The FASEB Journal
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Activation of the DNA Damage Response Pathway and the Role of NBS1 in Response to Hedgehog Signaling Inhibition

2012 The FASEB Journal
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Blocking Hedgehog Survival Signaling at the Level of the GLI Genes Induces DNA Damage and Extensive Cell Death in Human Colon Carcinoma Cells

2011 Cancer Research
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Identification of STAT3-independent regulatory effects for protein inhibitor of activated STAT3 by binding to novel transcription factors

2011 Cancer Biology & Therapy
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