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Una ODoherty

University of Pennsylvania

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Gastrointestinal Manifestation of Severe SARS-CoV-2 Infection in an Immunocompromised Dog

2021
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Naive infection predicts reservoir diversity and is a formidable hurdle to HIV eradication.

2021 JCI insight
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Femtomolar SARS-CoV-2 Antigen Detection Using the Microbubbling Digital Assay with Smartphone Readout Enables Antigen Burden Quantitation and Dynamics Tracking

2021
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Persistence of an intact HIV reservoir in phenotypically naive T cells

2020 JCI insight
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Next generation sequencing in a direct infection model reveals important parallels to in vivo reservoir dynamics

2019 Journal of virus eradication
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Longitudinal HIV sequencing reveals reservoir expression leading to decay which is obscured by clonal expansion

2019 Nature Communications
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Longitudinal sequencing reveals multiphasic decay of HIV reservoir

2019 Journal of virus eradication
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Longitudinal proviral sequencing provides a window into selection pressures exerted on infected cells and provides an upper bound estimate of proviral half-lives which are influenced by expression and splicing potential

2019 Journal of virus eradication
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HLA-C downregulation by HIV-1 adapts to host HLA genotype

2018 PLOS Pathogens
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Measuring integrated HIV DNA ex vivo and in vitro provides insights about how reservoirs are formed and maintained

2018 Retrovirology
- Marilia Rita Pinzone
- Una ODoherty
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