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G. J. Pronk

Utrecht University

5

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Insulin-induced tyrosine phosphorylation of a M(r) 70,000 protein revealed by association with the Src homology 2 (SH2) and SH3 domains of p120GAP and Grb2

1996 Cell Growth & Differentiation
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A mutant insulin receptor induces formation of a Shc-growth factor receptor bound protein 2 (Grb2) complex and p21ras-GTP without detectable interaction of insulin receptor substrate 1 (IRS1) with Grb2. Evidence for IRS1-independent p21ras-GTP formation.

1994 Journal of Biological Chemistry
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Involvement of Shc in insulin- and epidermal growth factor-induced activation of p21ras

1994 Molecular and Cellular Biology
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Insulin-induced phosphorylation of the 46- and 52-kDa Shc proteins.

1993 Journal of Biological Chemistry
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