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Zhiming Zhang

Pfizer

33

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1-Methyl-1H-pyrrole-2-carbonitrile containing tetrahydronaphthalene derivatives as non-steroidal progesterone receptor antagonists

2010 Bioorganic & Medicinal Chemistry Letters
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Novel progesterone receptor modulators with gene selective and context-dependent partial agonism.

2009 Biochemical Pharmacology
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7-Aryl 1,5-dihydro-benzo[e][1,4]oxazepin-2-ones and analogs as non-steroidal progesterone receptor antagonists

2008 Bioorganic & Medicinal Chemistry
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SAR studies of 6-(arylamino)-4,4-disubstituted-1-methyl-1,4-dihydro-benzo[d][1,3]oxazin-2-ones as progesterone receptor antagonists

2007 Bioorganic & Medicinal Chemistry Letters
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Selective and opposing actions of progesterone receptor isoforms in human endometrial stromal cells.

2006 Molecular and Cellular Endocrinology
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Down-regulation of endometrial matrix metalloproteinase-3 and -7 expression in vitro and therapeutic regression of experimental endometriosis in vivo by a novel nonsteroidal progesterone receptor agonist, tanaproget.

2006 The Journal of Clinical Endocrinology and Metabolism
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Development of a mouse model of mammary gland versus uterus tissue selectivity using estrogen- and progesterone-regulated gene markers.

2006 The Journal of Steroid Biochemistry and Molecular Biology
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Synthesis and Structure−Activity Relationship of Novel 6-Aryl-1,4- dihydrobenzo[d][1,3]oxazine-2-thiones as Progesterone Receptor Modulators Leading to the Potent and Selective Nonsteroidal Progesterone Receptor Agonist Tanaproget#

2005 Journal of Medicinal Chemistry
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SAR studies of 6-aryl-1,3-dihydrobenzimidazol-2-ones as progesterone receptor antagonists

2005 Bioorganic & Medicinal Chemistry Letters
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Regulation of gene expression by PRA-910, a novel progesterone receptor modulator, in T47D cells

2003 Steroids
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