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Yukiko Nakajima

University of Tokyo

15

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587

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Polymorphic tandem repeat sequences of the thymidylate synthase gene correlates with cellular-based sensitivity to fluoropyrimidine antitumor agents

2005 Cancer Chemotherapy and Pharmacology
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Haplotype structures of EPHX1 and their effects on the metabolism of carbamazepine-10,11-epoxide in Japanese epileptic patients.

2005 European Journal of Clinical Pharmacology
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Five novel single nucleotide polymorphisms in the EPHX1 gene encoding microsomal epoxide hydrolase.

2003 Drug Metabolism and Pharmacokinetics
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Six Novel Nonsynonymous CYP1A2 Gene Polymorphisms: Catalytic Activities of the Naturally Occurring Variant Enzymes

2003 Journal of Pharmacology and Experimental Therapeutics
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Eleven novel single nucleotide polymorphisms in the NR1I2 (PXR) gene, four of which induce non-synonymous amino acid alterations.

2002 Drug Metabolism and Pharmacokinetics
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Prediction of in Vivo Drug-Drug Interactions between Tolbutamide and Various Sulfonamides in Humans Based on in Vitro Experiments

2000 Drug Metabolism and Disposition
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Physiologically-based Pharmacokinetic Analysis of Grepafloxacin

2000 Biological & Pharmaceutical Bulletin
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21C-04-3 Is It Possible to Quantitatively Predict In Vivo Drug Metabolizing Activity of Cytochrome P450 in Human Liver from In Vitro Metabolic Studies ?

1999 Journal of Toxicological Sciences
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PREDICTION OF THE IN VIVO DRUG METABOLIZING ACTIVITY IN HUMAN LIVER FROM IN VITRO DATA ON METABOLISM : THE USE OF HUMAN LIVER MICROSOMES AND RECOMBINANT HUMAN CYP ISOZYMES

1999 Drug Metabolism and Pharmacokinetics
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QUANTITATIVE PREDICTION OF IN VIVO METABOLIC CLEARANCE AND DRUG-DRUG INTERACTIONS IN HUMANS BASED ON IN VTIRO STUDIES

1997 Drug Metabolism and Pharmacokinetics
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Citations (1)