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Graeme R. Guy

National University of Singapore

66

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Intersectin enhances Cbl ubiquitylation of epidermal growth factor receptor through regulation of Sprouty2‐Cbl interaction

2013 The FASEB Journal
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Structure of a novel phosphotyrosine-binding domain in Hakai that targets E-cadherin

2012 The EMBO Journal
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Intersectin 1 Enhances Cbl Ubiquitylation of Epidermal Growth Factor Receptor through Regulation of Sprouty2-Cbl Interaction

2012 Molecular and Cellular Biology
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Direct Association of Sprouty-related Protein with an EVH1 Domain (SPRED) 1 or SPRED2 with DYRK1A Modifies Substrate/Kinase Interactions

2010 Journal of Biological Chemistry
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Sprouty proteins: modified modulators, matchmakers or missing links?

2009 Journal of Endocrinology
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Sprouty2 Interacts with Protein Kinase Cδ and Disrupts Phosphorylation of Protein Kinase D1

2009 Journal of Biological Chemistry
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Tesk1 interacts with Spry2 to abrogate its inhibition of ERK phosphorylation downstream of receptor tyrosine kinase signaling.

2008 Journal of Biological Chemistry
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Crystal structure of c-Cbl-TKB domain complexed with its binding motif in EGF receptor'

2008
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Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Sprouty2

2008
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Direct Binding of PP2A to Sprouty2 and Phosphorylation Changes Are a Prerequisite for ERK Inhibition Downstream of Fibroblast Growth Factor Receptor Stimulation

2007 Journal of Biological Chemistry
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Citations (51)