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Paola Pellegrini

Karolinska Institutet

18

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520

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Induction of ER Stress in Acute Lymphoblastic Leukemia Cells by the Deubiquitinase Inhibitor VLX1570.

2020 International Journal of Molecular Sciences
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Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system

2019 Scientific Reports
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A drug screening assay on cancer cells chronically adapted to acidosis

2018 Cancer Cell International
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The deubiquitinase inhibitor b-AP15 induces strong proteotoxic stress and mitochondrial damage

2018 Biochemical Pharmacology
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Citations (17)
Acute lymphoblastic leukemia cells are sensitive to disturbances in protein homeostasis induced by proteasome deubiquitinase inhibition

2017 Oncotarget
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Tumor acidosis enhances cytotoxic effects and autophagy inhibition by salinomycin on cancer cell lines and cancer stem cells

2016 Oncotarget
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Altered pH gradient at the plasma membrane of osteosarcoma cells is a key mechanism of drug resistance

2016 Oncotarget
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Cell crowding induces interferon regulatory factor 9, which confers resistance to chemotherapeutic drugs.

2015 International Journal of Cancer
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Acidic extracellular pH neutralizes the autophagy-inhibiting activity of chloroquine: Implications for cancer therapies

2014 Autophagy
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SIRT1 and SIRT2 inhibition impairs pediatric soft tissue sarcoma growth

2014 Cell Death and Disease
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Citations (29)