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Barbora Mrázová
Barbora Mrázová
Charles University in Prague
Biochemistry
Enzyme
Cytochrome P450
Chemistry
Cytochrome b
5
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85
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Cytochrome b5 shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy
2011
Biochemical Pharmacology
Věra Kotrbová
Barbora Mrázová
Michaela Moserová
Václav Martínek
Petr Hodek
Jiří Hudeček
Eva Frei
Marie Stiborová
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Citations (41)
Role of cytochromes P450 and peroxidases in metabolism of the anticancer drug ellipticine: additional evidence of their contribution to ellipticine activation in rat liver, lung and kidney
2010
Neuro endocrinology letters
Marie Stiborová
Michaela Moserová
Barbora Mrázová
Kotrbová
Eva Frei
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Preparation of apo-cytochrome b5 utilizing heme transfer to apo-myoglobin
2009
Neuro endocrinology letters
Barbora Mrázová
Martinek
Marketa Martinkova
Miroslav Šulc
Eva Frei
Marie Stiborová
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Optimalization of preparation of apo-cytochrome b(5) utilizing apo-myoglobin.
2008
Interdisciplinary Toxicology
Barbora Mrázová
Marketa Martinkova
Václav Martínek
Eva Frei
Marie Stiborová
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The anticancer drug ellipticine is a potent inducer of rat cytochromes P450 1A1 and -1A2, thereby modulating its own metabolism
2007
Drug Metabolism and Disposition
Dagmar Aimová
Lucie Svobodová
Věra Kotrbová
Barbora Mrázová
Petr Hodek
Jiří Hudeček
Radka Vaclavikova
Eva Frei
Marie Stiborová
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Citations (33)
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