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Zhigang Yu

University of Michigan

19

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946

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MEF2 impairment underlies skeletal muscle atrophy in polyglutamine disease.

2020 Acta Neuropathologica
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Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor

2019 Nature Communications
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Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction

2018 Journal of Clinical Investigation
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Rescue of Metabolic Alterations in AR113Q Skeletal Muscle by Peripheral Androgen Receptor Gene Silencing

2016 Cell Reports
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Disrupting SUMOylation Enhances Transcriptional Function and Ameliorates Polyglutamine Androgen Receptor-Mediated Disease

2015 Journal of Clinical Investigation
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Prenatal flutamide enhances survival in a myogenic mouse model of spinal bulbar muscular atrophy

2011 Neurodegenerative Diseases
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Macroautophagy Is Regulated by the UPR-Mediator CHOP and Accentuates the Phenotype of SBMA Mice

2011 PLOS Genetics
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Microarray Analysis of Gene Expression by Skeletal Muscle of Three Mouse Models of Kennedy Disease/Spinal Bulbar Muscular Atrophy

2010 PLOS ONE
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Altered RNA splicing contributes to skeletal muscle pathology in Kennedy disease knock-in mice.

2009 Disease Models & Mechanisms
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Overexpression of wild-type androgen receptor in muscle recapitulates polyglutamine disease

2007 Proceedings of the National Academy of Sciences of the United States of America
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Citations (136)