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Xin Smith

University of Cambridge

13

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379

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LFA-1 activates focal adhesion kinases FAK1/PYK2 to generate LAT-GRB2-SKAP1 complexes that terminate T-cell conjugate formation

2017 Nature Communications
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T-cell immune adaptor SKAP1 regulates the induction of collagen-induced arthritis in mice

2016 Immunology Letters
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Receptor (TCR) Activation of LFA-1 Protein Complex Formation for T Cell RapL Membrane Localization and Rap1 SKAP1 Protein PH Domain Determines Immunology:

2014
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The chemokine CXCL12 generates costimulatory signals in T cells to enhance phosphorylation and clustering of the adaptor protein SLP-76.

2013 Science Signaling
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SKAP1 Protein PH Domain Determines RapL Membrane Localization and Rap1 Protein Complex Formation for T Cell Receptor (TCR) Activation of LFA-1

2011 Journal of Biological Chemistry
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Cell adhesion in immunity (WS-103) Chairpersons: Tatsuo Kinashi, Sirpa Jalkanen

2010 International Immunology
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CTLA-4 disrupts ZAP70 microcluster formation with reduced T cell/APC dwell times and calcium mobilization

2008 European Journal of Immunology
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Ox40 (CD134) blockade inhibits the co-stimulatory cascade and promotes heart allograft survival

2004 Transplantation
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Selective blockade of IL-15 by soluble IL-15 receptor alpha-chain enhances cardiac allograft survival

2000 Journal of Immunology
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