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Grant R. Whitman

University of Washington

23

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268

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A short-term treatment with BKI-1294 does not protect foetuses from sheep experimentally infected with Neospora caninum tachyzoites during pregnancy.

2021 International Journal for Parasitology-Drugs and Drug Resistance
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Endochin-like quinolones (ELQs) and bumped kinase inhibitors (BKIs): Synergistic and additive effects of combined treatments against Neospora caninum infection in vitro and in vivo.

2021 International Journal for Parasitology-Drugs and Drug Resistance
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In vitro activity, safety and in vivo efficacy of the novel bumped kinase inhibitor BKI-1748 in non-pregnant and pregnant mice experimentally infected with Neospora caninum tachyzoites and Toxoplasma gondii oocysts

2021 International Journal for Parasitology-Drugs and Drug Resistance
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Pyrrolopyrimidine Bumped Kinase Inhibitors for the Treatment of Cryptosporidiosis.

2021 ACS Infectious Diseases
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One Health Therapeutics: Target-Based Drug Development for Cryptosporidiosis and Other Apicomplexa Diseases

2020 Veterinary Parasitology
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Bumped Kinase Inhibitors as therapy for apicomplexan parasitic diseases: lessons learned.

2020 International Journal for Parasitology
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nComparative assessment of the effects of bumped kinase inhibitors on early zebrafish embryo development and pregnancy in mice.

2020 International Journal of Antimicrobial Agents
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Pharmacokinetics and In Vivo Efficacy of Pyrazolopyrimidine, Pyrrolopyrimidine, and 5-Aminopyrazole-4-Carboxamide Bumped Kinase Inhibitors against Toxoplasmosis

2019 The Journal of Infectious Diseases
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Bumped kinase inhibitor 1369 is effective against Cystoisospora suis in vivo and in vitro

2019 International Journal for Parasitology-Drugs and Drug Resistance
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P-glycoprotein mediated efflux reduces the in vivo efficacy of a therapeutic targeting the gastrointestinal parasite Cryptosporidium

2019 The Journal of Infectious Diseases
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