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Alan R. Fersht

Laboratory of Molecular Biology
College of Science and Technology
University of Cambridge

239

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AlphaFold - A personal perspective on the impact of Machine Learning.

2021 Journal of Molecular Biology
- Alan R. Fersht
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SLMP53-2 Restores Wild-Type-Like Function to Mutant p53 through Hsp70: Promising Activity in Hepatocellular Carcinoma

2019 Cancers
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ChemBioChem@20—Some Reflections

2019 ChemBioChem
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Mutant p53 as A Therapeutic Target for the Treatment of Triple-Negative Breast Cancer: Preclinical Investigation with the Anti-p53 Drug, PK11007

2018 Cancer Letters
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Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C and show anticancer activity in p53-Y220C cell lines.

2018 European Journal of Medicinal Chemistry
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Targeting mutant p53 with PK11007: A new approach for the treatment of patients with triple-negative breast cancer?

2017 Journal of Clinical Oncology
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Closed dimer of human ATM (Ataxia telangiectasia mutated)

2017
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Open protomer of human ATM (Ataxia telangiectasia mutated)

2017
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An in silico algorithm for identifying stabilizing pockets in proteins: test case, the Y220C mutant of the p53 tumor suppressor protein.

2016 Protein Engineering Design & Selection
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Design of a molecular support for cryo-EM structure determination

2016 Proceedings of the National Academy of Sciences of the United States of America
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Citations (75)