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Yuxing Zhao

Duke University

10

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Akt Requires Glucose Metabolism to Suppress Puma Expression and Prevent Apoptosis of Leukemic T Cells

2011 Journal of Biological Chemistry
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Abstract LB-261: Maintenance of aerobic glycolysis provides selective protection from apoptosis upon loss of growth signals or inhibition of BCR-Abl through suppression of p53 activation

2011 Cancer Research
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Aerobic glycolysis suppresses p53 activity to provide selective protection from apoptosis upon loss of growth signals or inhibition of BCR-Abl.

2010 Cancer Research
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Autophagy provides nutrients but can lead to chop-dependent induction of bim to sensitize growth factor-deprived cells to apoptosis.

2009 Molecular Biology of the Cell
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Mechanisms and Methods in Glucose Metabolism and Cell Death

2008 Methods in Enzymology
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Glucose Metabolism Attenuates p53 and Puma-dependent Cell Death upon Growth Factor Deprivation

2008 Journal of Biological Chemistry
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IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T cell survival

2008 Blood
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Glycogen Synthase Kinase 3α and 3β Mediate a Glucose-Sensitive Antiapoptotic Signaling Pathway To Stabilize Mcl-1

2007 Molecular and Cellular Biology
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