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Shunsuke Kageyama

Ajinomoto

14

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325

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Structure-activity relationship study, target identification, and pharmacological characterization of a small molecular IL-12/23 inhibitor, APY0201.

2014 Bioorganic & Medicinal Chemistry
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A novel, orally active alpha 4 integrin antagonist, AJM300 prevents the development of experimental colitis induced by adoptive transfer of IL-10 deficient CD4(+) T cells in mice.

2012 Journal of Pharmacology and Experimental Therapeutics
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Tu1864 A Novel Orally Active Phosphatidylinositol 3-Phosphate 5-Kinase (Pikfyve) Inhibitor Ameliorates Mouse Colitis by Inhibition of IL-12 and IL-23 Production From Macrophages

2012 Gastroenterology
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An Orally Available Alpha 4 (α4) Integrin Antagonist AJM300 Increases the Peripheral Lymphocyte Counts: The Relationship Between Pharmacokinetics/Pharmacodynamics (PK/PD) and Efficacy Against Colitis Model in Mice

2011 Gastroenterology
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M1647 An Orally Active Alpha4 Integrin Antagonist AJM300 Prevents the Development of Experimental Colitis Induced By Adoptive Transfer of IL-10 Deficient CD4+ T Cells in Mice

2009 Gastroenterology
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Nouveau derive phenylalanine

2004
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Nouveau derive phenylalanines

2004
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Effect of a humanized monoclonal antibody to von Willebrand factor in a canine model of coronary arterial thrombosis

2002 European Journal of Pharmacology
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Anti-Human vWF Monoclonal Antibody, AJvW-2 Fab, Inhibits Repetitive Coronary Artery Thrombosis without Bleeding Time Prolongation in Dogs

2001 Thrombosis Research
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Vefahren for production of peptide subunits of polymeric proteins

2000
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