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Akalushi Muthukumarana

Boehringer Ingelheim

10

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140

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Physical Properties and Effect in a Battery of Safety Pharmacology Models for Three Structurally Distinct Enteric Polymers Employed as Spray-Dried Dispersion Carriers

2016 Frontiers in Pharmacology
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CCR1 Plays a Critical Role in Modulating Pain through Hematopoietic and Non-Hematopoietic Cells

2014 PLOS ONE
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Effect of Differentially Selective S1P Receptor Agonists on Cardiovascular Function after Acute and Long‐Term Administration in Rat Suggestive of Subtype‐Specific Bradycardia (S1P 1 ) and Hypertension (S1P 3 )

2012 The FASEB Journal
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Strategic integration of in vivo cardiovascular models during lead optimization: predictive value of 4 models independent of species, route of administration, and influence of anesthesia.

2012 Journal of Cardiovascular Pharmacology
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The Clinically-tested S1P Receptor Agonists, FTY720 and BAF312, Demonstrate Subtype-Specific Bradycardia (S1P1) and Hypertension (S1P3) in Rat

2012 PLOS ONE
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Functional biomarkers of musculoskeletal syndrome (MSS) for early in vivo screening of selective MMP-13 inhibitors

2011 Journal of Pharmacological and Toxicological Methods
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Translation of in vitro adrenergic receptor binding in selectivity screen to in vivo functional cardiovascular effects during lead optimization

2011 Journal of Pharmacological and Toxicological Methods
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