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Sean Kim

Bristol-Myers Squibb

16

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944

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Pharmacokinetic-Pharmacodynamic Modeling of Rifampicin-Mediated Cyp3a11 Induction in Steroid and Xenobiotic X Receptor Humanized Mice

2011 Journal of Pharmacology and Experimental Therapeutics
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Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers

2011 Proceedings of the National Academy of Sciences of the United States of America
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Anticipating and Minimizing Drug Interactions in a Drug Discovery and Development Setting: An Industrial Perspective

2010
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Evaluating and Predicting Human Cytochrome P450 Enzyme Induction

2010
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Discovery and evaluation of 4-(2-(4-chloro-1H-pyrazol-1-yl)ethylamino)-3-(6-(1-(3-fluoropropyl)piperidin-4-yl)-4-methyl-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one (BMS-695735), an orally efficacious inhibitor of insulin-like growth factor-1 receptor kinase with broad spectrum in vivo antitumor activity.

2008 Journal of Medicinal Chemistry
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Quantitative relationship between rifampicin exposure and induction of Cyp3a11 in SXR humanized mice: extrapolation to human CYP3A4 induction potential.

2008 Drug Metabolism Letters
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Expanding the Roles for Pregnane X Receptor in Cancer: Proliferation and Drug Resistance in Ovarian Cancer

2008 Clinical Cancer Research
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Is celecoxib an inducer of cytochrome P450 3A4 in subjects carrying the CYP2C9*3 allele?

2006 Clinical Pharmacology & Therapeutics
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Stem cells, immortalized cells and primary cells in ADMET assays

2006 Drug Discovery Today: Technologies
- Michael Sinz
- Sean Kim
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Correlation of High-Throughput Pregnane X Receptor (PXR) Transactivation and Binding Assays

2004 Journal of Biomolecular Screening
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Citations (56)