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H Brown

County Durham and Darlington NHS Foundation Trust

11

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333

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PWE-008 Placide: Probiotics in the Prevention of Antibiotic Associated Diarrhoea (AAD) and Clostridium Difficile Associated Diarrhoea (CDD) in Elderly Patients Admitted to Hospital – Results of a Large Multi-Centre RCT in the UK

2013 Gut
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Participant flow chart

2013
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Information regarding exposure to antibiotics according to centre and severe adverse events in the two intervention arms classified according to MedDRA preferred term and actions taken regarding the trial interventions

2013
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A high-dose preparation of lactobacilli and bifidobacteria in the prevention of antibiotic-associated and Clostridium difficile diarrhoea in older people admitted to hospital: a multicentre, randomised, double-blind, placebo-controlled, parallel arm trial (PLACIDE)

2013 Health Technology Assessment
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Classification of antibiotics (according to British National Formulary 2012)

2013
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Details of wards involved in the recruitment of patients by centre

2013
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Criteria for severity of Clostridium difficile infection

2013
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Patient information sheet, consent form, advocate information sheet and advocate assent form

2013
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Lactobacilli and bifidobacteria in the prevention of antibiotic-associated diarrhoea and Clostridium difficile diarrhoea in older inpatients (PLACIDE): a randomised double-blind, placebo-controlled, multicentre trial

2013 The Lancet
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A multicentre randomised controlled trial evaluating lactobacilli and bifidobacteria in the prevention of antibiotic-associated diarrhoea in older people admitted to hospital: the PLACIDE study protocol

2012 BMC Infectious Diseases
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