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Tomoki Yoneyama

Takeda Pharmaceutical Company

9

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59

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Leveraging a physiologically-based quantitative translational modeling platform for designing B cell maturation antigen-targeting bispecific T cell engagers for treatment of multiple myeloma

2022 PLOS Computational Biology
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Mechanistic Multilayer Quantitative Model for Nonlinear Pharmacokinetics, Target Occupancy and Pharmacodynamics (PK/TO/PD) Relationship of D-Amino Acid Oxidase Inhibitor, TAK-831 in Mice

2020 Pharmaceutical Research
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Quantitative Systems Pharmacology approaches for Immuno‐oncology: adding virtual patients to the development paradigm

2020 Clinical Pharmacology & Therapeutics
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A citrulline based translational population system toxicology model for gastrointestinal related adverse events associated with anti‐cancer treatments

2019
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A validated simultaneous quantification method for vonoprazan (TAK-438F) and its 4 metabolites in human plasma by the liquid chromatography-tandem mass spectrometry

2016 Journal of Chromatography B
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Tiered Approaches to Chromatographic Bioanalytical Method Performance Evaluation: Recommendation for Best Practices and Harmonization from the Global Bioanalysis Consortium Harmonization Team

2015 Aaps Journal
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Retrospective data analysis and proposal of a practical acceptance criterion for inter-laboratory cross-validation of bioanalytical methods using liquid chromatography/tandem mass spectrometry.

2014 Aaps Journal
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Studies on 1-alkylamine adduct formation in electrospray ionization mass spectrometry for quantitative analysis

2008 Journal of Pharmaceutical and Biomedical Analysis
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