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R. John Booth
R. John Booth
Pfizer
Enzyme
Kinase
Biochemistry
Chemistry
Carbazole
4
Papers
291
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Gemcitabine sensitization by checkpoint kinase 1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells
2009
Molecular Cancer Therapeutics
Leslie A. Parsels
Meredith A. Morgan
Daria M. Tanska
Joshua D. Parsels
Brian D. Palmer
R. John Booth
William A. Denny
Christine E. Canman
Alan J. Kraker
Theodore S. Lawrence
Jonathan Maybaum
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Citations (119)
Synthesis and structure-activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases.
2008
European Journal of Medicinal Chemistry
Jeff B. Smaill
Edward N. Baker
R. John Booth
Alexander James Bridges
James M. Dickson
Ellen M. Dobrusin
Ivan Ivanovic
Alan J. Kraker
Ho H. Lee
Elizabeth A. Lunney
Daniel F. Ortwine
Brian D. Palmer
John Quin
Christopher J. Squire
Andrew M. Thompson
William A. Denny
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Citations (19)
Synthesis and structure-activity relationships of soluble 8-substituted 4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of the Wee1 and Chk1 checkpoint kinases.
2008
Bioorganic & Medicinal Chemistry Letters
Jeff B. Smaill
Ho H. Lee
Brian D. Palmer
Andrew M. Thompson
Christopher J. Squire
Edward N. Baker
R. John Booth
Alan J. Kraker
Ken Hook
William A. Denny
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Citations (24)
Pyrido[2,3-d]pyrimidin-7-ones as specific inhibitors of cyclin-dependent kinase 4.
2005
Journal of Medicinal Chemistry
Scott Norman Vanderwel
Patricia J. Harvey
Dennis Joseph Mcnamara
Joseph Thomas Repine
Paul R. Keller
John Quin
R. John Booth
William L. Elliott
Ellen Myra Dobrusin
and David W. Fry
Peter L. Toogood
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Citations (129)
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