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Denise L. Holzle
Denise L. Holzle
University of Illinois at Chicago
Chemistry
Binding site
Stereochemistry
Biochemistry
Photoaffinity Labels
4
Papers
211
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Design, Synthesis, Docking, and Biological Evaluation of Novel Diazide-containing Isoxazole- and Pyrazole-based Histone Deacetylase Probes
2011
Journal of Medicinal Chemistry
Raghupathi Neelarapu
Denise L. Holzle
Subash Velaparthi
He Bai
Michael Brunsteiner
Sylvie Y. Blond
Pavel A. Petukhov
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Citations (68)
Use of molecular modeling, docking, and 3D-QSAR studies for the determination of the binding mode of benzofuran-3-yl-(indol-3-yl)maleimides as GSK-3β inhibitors
2009
Journal of Molecular Modeling
Ki Hwan Kim
Irina N. Gaisina
Franck Gallier
Denise L. Holzle
Sylvie Y. Blond
Andrew D. Mesecar
Alan P. Kozikowski
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Citations (11)
Binding ensemble profiling with photoaffinity labeling (BEProFL) approach: mapping the binding poses of HDAC8 inhibitors.
2009
Journal of Medicinal Chemistry
Bai He
Subash Velaparthi
Gilles Pieffet
Chris Pennington
Aruna Mahesh
Denise L. Holzle
Michael Brunsteiner
Richard B. van Breemen
Sylvie Y. Blond
Pavel A. Petukhov
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Citations (39)
From a Natural Product Lead to the Identification of Potent and Selective Benzofuran-3-yl-(indol-3-yl)maleimides as Glycogen Synthase Kinase 3β Inhibitors that Suppress Proliferation and Survival of Pancreatic Cancer Cells
2009
Journal of Medicinal Chemistry
Irina N. Gaisina
Franck Gallier
Andrei V. Ougolkov
Ki Hwan Kim
Toru Kurome
Songpo Guo
Denise L. Holzle
Doris N. Luchini
Sylvie Y. Blond
Daniel D. Billadeau
Alan P. Kozikowski
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Citations (93)
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