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Anthony D R Angell
Anthony D R Angell
GlaxoSmithKline
Pharmacology
Biochemistry
Chemistry
In vitro
In vivo
5
Papers
134
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Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor.
2011
Bioorganic & Medicinal Chemistry Letters
Robert J. Young
Wendy Karen Alderton
Anthony D R Angell
Paul John Beswick
David W. Brown
C. Lynn Chambers
Miriam C. Crowe
John Dawson
Christopher Charles Frederick Hamlett
Simon T. Hodgson
Savvas Kleanthous
Richard G. Knowles
Linda J. Russell
Richard Stocker
James Michael Woolven
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Citations (1)
GSK256066, an Exceptionally High-Affinity and Selective Inhibitor of Phosphodiesterase 4 Suitable for Administration by Inhalation: In Vitro, Kinetic, and In Vivo Characterization
2011
Journal of Pharmacology and Experimental Therapeutics
Catherine Tralau-Stewart
Richard A. Williamson
Anthony T. Nials
Michele H. Gascoigne
John Dawson
Graham Hart
Anthony D R Angell
Yemisi E. Solanke
Fiona S. Lucas
Joanne Wiseman
Peter Ward
Lisa E. Ranshaw
Richard G. Knowles
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Citations (50)
In Vitro Characterisation of GSK256066, an Exceptionally High Affinity and Selective Inhibitor of PDE4 Suitable for Topical Administration.
2009
ATS | American Thoracic Society International Conference
Richard G. Knowles
Catherine Tralau-Stewart
John Dawson
Gj Hart
Anthony D R Angell
Yemisi E. Solanke
Fiona S. Lucas
Joanne Wiseman
Peter Ward
Richard A. Williamson
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Citations (6)
GW274150 and GW273629 are potent and highly selective inhibitors of inducible nitric oxide synthase in vitro and in vivo
2005
British Journal of Pharmacology
Wendy Karen Alderton
Anthony D R Angell
Caroline Craig
John Dawson
Edward P. Garvey
Salvador Moncada
Jayne Monkhouse
Daryl D. Rees
Linda J. Russell
Rachel J. Russell
Sheila Schwartz
Neil Waslidge
Richard G. Knowles
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Citations (72)
GW273629 is a highly selective, short-acting iNOS (NOS-2) inhibitor both in vitro and in vivo: beneficial effects in endotoxin shock
2000
Richard G. Knowles
John Dawson
N Waslidge
Rachel J. Russell
Anthony D R Angell
C. Craig
Sheila Schwartz
S Evans
Brendan J.R. Whittle
Edward P. Garvey
Jayne Monkhouse
Salvador Moncada
Daryl D. Rees
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Citations (5)
1