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Ralph Adams

UCB

25

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245

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Bimekizumab, a Novel Humanized IgG1 Antibody That Neutralizes Both IL-17A and IL-17F

2020 Frontiers in Immunology
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Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signaling.

2017 Scientific Reports
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Biophysical and cellular characterisation of a junctional epitope antibody that locks IL-6 and gp80 together in a stable complex: implications for new therapeutic strategies

2017
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Extending the half-life of a fab fragment through generation of a humanized anti-human serum albumin Fv domain: An investigation into the correlation between affinity and serum half-life

2016 mAbs
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Anticorps anti-ap2 et agents de liaison à l'antigène utilisables en vue du traitement d'affections métaboliques

2016
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Fab-dsFv: A bispecific antibody format with extended serum half-life through albumin binding

2016 mAbs
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Crystal structure of the Fab portion of Olokizumab in complex with IL- 6

2014
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Discovery and characterization of olokizumab: a humanized antibody targeting interleukin-6 and neutralizing gp130-signaling.

2014 mAbs
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In vitro and in vivo characterisation of anti-murine IL-13 antibodies recognising distinct functional epitopes.

2009 International Immunopharmacology
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High-Throughput Screening for High Affinity Antibodies

2009 Journal of Laboratory Automation
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Citations (21)