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Qing-cheng Wang

Laboratory of Molecular Biology

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An immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes

2008 Proceedings of the National Academy of Sciences of the United States of America
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Releasable PEGylation of mesothelin targeted immunotoxin SS1P achieves single dosage complete regression of a human carcinoma in mice.

2007 Bioconjugate Chemistry
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Genetic Engineering of Glomerular Sclerosis in the Mouse via Control of Onset and Severity of Podocyte-Specific Injury

2005 Journal of The American Society of Nephrology
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Humoral Immune Response to Mesothelin in Mesothelioma and Ovarian Cancer Patients

2005 Clinical Cancer Research
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In Vitro and in Vivo Cytotoxic Activities of Recombinant Immunotoxin 8H9(Fv)- PE38 against Breast Cancer, Osteosarcoma, and Neuroblastoma

2004 Cancer Research
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Cytotoxic Activity of Disulfide-stabilized Recombinant Immunotoxin RFB4(dsFv)-PE38 (BL22) toward Fresh Malignant Cells from Patients with B-Cell Leukemias

2000 Clinical Cancer Research
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Anti-tumor activity of K1-LysPE38QQR, an immunotoxin targeting Mesothelin, a cell-surface antigen overexpressed in ovarian cancer and malignant mesothelioma

2000 Journal of Immunotherapy
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Inhibition of TNF-α Produced by Kupffer Cells Protects Against the Nonspecific Liver Toxicity of Immunotoxin Anti-Tac(Fv)-PE38, LMB-2

2000 Journal of Immunology
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Complete regression of human B-cell lymphoma xenografts in mice treated with recombinant anti-CD22 immunotoxin RFB4(dsFv)-PE38 at doses tolerated by cynomolgus monkeys.

1999 International Journal of Cancer
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Complete regression of human B-cell lymphoma xenografts in mice treated with recombinant anti-CD22 immunotoxin RFB4(dsFv)-PE38 at doses tolerated by cynomolgus monkeys This article is a US Government work and, as such, is in the public domain in the United States of America.

1999 International Journal of Cancer
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Citations (6)