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Takao Kiyoi

Merck & Co.

12

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176

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Low brain penetrant CB1 receptor agonists for the treatment of neuropathic pain.

2012 Bioorganic & Medicinal Chemistry Letters
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Synthesis of hexahydro[2]benzopyrano[4,3-c]pyridines as serotonin 5-HT2C receptor agonists via intramolecular hetero Diels–Alder reactions

2011 Tetrahedron Letters
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Design, synthesis, and structure–activity relationships of indole-3-heterocycles as agonists of the CB1 receptor

2011 Bioorganic & Medicinal Chemistry Letters
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Design, synthesis and structure–activity relationships of (indo-3-yl) heterocyclic derivatives as agonists of the CB1 receptor. Discovery of a clinical candidate

2011 Bioorganic & Medicinal Chemistry Letters
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Stereoselective synthesis of tetrahydro-2H-[2]benzopyrano[3,4-c]pyrrol-3-ones and related compounds as precursors of serotonin 5-HT2C receptor agonists

2011 Tetrahedron Letters
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Synthesis of Hexahydro[2]benzopyrano[4,3-c]pyridines as Serotonin 5-HT2C Receptor Agonists via Intramolecular Hetero Diels—Alder Reactions.

2011 ChemInform
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Discovery of potent and orally bioavailable heterocycle-based cannabinoid CB1 receptor agonists

2011 Bioorganic & Medicinal Chemistry Letters
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Sythesis of Serotonin Antagonists Using an IntramolecularDiels-Alder Approach

2011 Synfacts
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Design, synthesis, and structure–activity relationship study of conformationally constrained analogs of indole-3-carboxamides as novel CB1 cannabinoid receptor agonists

2010 Bioorganic & Medicinal Chemistry Letters
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Design, synthesis, and structure-activity relationship study of bicyclic piperazine analogs of indole-3-carboxamides as novel cannabinoid CB1 receptor agonists.

2010 Bioorganic & Medicinal Chemistry Letters
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Citations (17)