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Ivet Elias

Autonomous University of Barcelona

18

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814

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Adult mice are unresponsive to AAV8-Gremlin1 gene therapy targeting the liver.

2021 PLOS ONE
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FGF21 gene therapy as treatment for obesity and insulin resistance

2018 Embo Molecular Medicine
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BMP4 Gene Therapy in Mature Mice Reduces BAT Activation but Protects from Obesity by Browning Subcutaneous Adipose Tissue

2017 Cell Reports
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Long-Term Efficacy and Safety of Insulin and Glucokinase Gene Therapy for Diabetes: 8-Year Follow-Up in Dogs

2017 Molecular therapy. Methods & clinical development
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Long-term correction of diabetes in dogs after single intramuscular administration of adeno-associated viral vectors encoding for insulin and glucokinase

2016 New Biotechnology
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AAV-mediated Sirt1 overexpression in skeletal muscle activates oxidative capacity but does not prevent insulin resistance

2016 Molecular therapy. Methods & clinical development
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ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance.

2016 Diabetes
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AAV8-mediated Sirt1 gene transfer to the liver prevents high carbohydrate diet-induced nonalcoholic fatty liver disease

2014 Molecular therapy. Methods & clinical development
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New insights into adipose tissue VEGF-A actions in the control of obesity and insulin resistance

2013
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Response to Comment on: Elias et al. Adipose Tissue Overexpression of Vascular Endothelial Growth Factor Protects Against Diet-Induced Obesity and Insulin Resistance. Diabetes 2012;61:1801–1813

2013 Diabetes
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