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Dawn Waterhouse

BC Cancer Agency

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2020 Healthcare Management Forum
- Dawn Waterhouse
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Irinophore C™, a lipid nanoparticulate formulation of irinotecan, improves vascular function, increases the delivery of sequentially administered 5-FU in HT-29 tumors, and controls tumor growth in patient derived xenografts of colon cancer

2015 Journal of Controlled Release
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Determination of an optimal dosing schedule for combining Irinophore C™ and temozolomide in an orthotopic model of glioblastoma

2015 Journal of Controlled Release
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Abstract 824: In vivo efficacy of VAL-083 in the treatment of non-small cell lung cancer

2014 Cancer Research
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Irinophore C™, a lipid-based nanoparticulate formulation of irinotecan, is more effective than free irinotecan when used to treat an orthotopic glioblastoma model.

2012 Journal of Controlled Release
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Abstract 5261: Irinophore C, a liposomal formulation of irinotecan, has anti-vascular effects in primary tumors of colorectal cancer grown orthotopically in mice

2012 Cancer Research
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A low carbohydrate, high protein diet slows tumor growth and prevents cancer initiation.

2011 Cancer Research
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Vascular normalization in orthotopic glioblastoma following intravenous treatment with lipid-based nanoparticulate formulations of irinotecan (Irinophore C™), doxorubicin (Caelyx®) or vincristine.

2011 BMC Cancer
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Lipid-based nanoformulation of irinotecan: dual mechanism of action allows for combination chemo/angiogenic therapy

2011 Nanomedicine: Nanotechnology, Biology and Medicine
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Abstract B12: The effects of Irinophore C™ on the microenvironment and vasculature of a primary orthotopic model of colorectal cancer.

2011 Molecular Cancer Therapeutics
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