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Arun K. Ghosh

Purdue University
University of Illinois at Chicago
United States Military Academy

605

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Indole Chloropyridinyl Ester-Derived SARS-CoV-2 3CLpro Inhibitors: Enzyme Inhibition, Antiviral Efficacy, Structure-Activity Relationship, and X-ray Structural Studies.

2021 Journal of Medicinal Chemistry
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Design and synthesis of herboxidiene derivatives that potently inhibit in vitro splicing

2021 Organic and Biomolecular Chemistry
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Spliceostatins and Derivatives: Chemical Syntheses and Biological Properties of Potent Splicing Inhibitors.

2021 Journal of Natural Products
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Highly Diastereoselective Intramolecular Asymmetric Oxidopyrylium-olefin [5 + 2] Cycloaddition and Synthesis of 8-Oxabicyclo[3.2.1]oct-3-enone Containing Ring Systems.

2021 Journal of Organic Chemistry
- Arun K. Ghosh
- Monika Yadav
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Novel HIV PR inhibitors with C4-substituted bis-THF and bis-fluoro-benzyl target the two active site mutations of highly drug resistant mutant PRS17.

2021 Biochemical and Biophysical Research Communications
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U2 snRNA structure is influenced by SF3A and SF3B proteins but not by SF3B inhibitors.

2021 PLOS ONE
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A Structure-Based Discovery Platform for BACE2 and the Development of Selective BACE Inhibitors.

2021 ACS Chemical Neuroscience
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Herboxidiene Features That Mediate Conformation-Dependent SF3B1 Interactions to Inhibit Splicing.

2021 ACS Chemical Biology
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A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication.

2021 Nature Communications
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Chloropyridinyl Esters of Nonsteroidal Anti-Inflammatory Agents and Related Derivatives as Potent SARS-CoV-2 3CL Protease Inhibitors

2021 Molecules
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