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Ben Jiang
Ben Jiang
Amgen
Biochemistry
Chemistry
Hedgehog signaling pathway
Signal transduction
Smoothened
5
Papers
93
Citations
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Synthesis and optimization of novel 4,4-disubstituted cyclohexylbenzamide derivatives as potent 11β-HSD1 inhibitors
2011
Bioorganic & Medicinal Chemistry Letters
Daqing Sun
Zhulun Wang
Seb Caille
Michael DeGraffenreid
Felix Gonzalez Lopez De Turiso
Randall W. Hungate
Juan C. Jaen
Ben Jiang
Lisa D. Julian
Ron C. Kelly
Dustin L. McMinn
Jacob Kaizerman
Yosup Rew
Athena Sudom
Hua Tu
Stefania Ursu
Nigel Walker
Maren Willcockson
Xuelei Yan
Qiuping Ye
Jay P. Powers
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Citations (14)
Discovery of amide replacements that improve activity and metabolic stability of a bis-amide smoothened antagonist hit
2011
Bioorganic & Medicinal Chemistry Letters
Matthew Brown
Wade Aaron
Richard J. Austin
Angela Chong
Tom Huang
Ben Jiang
Jacob Kaizerman
Gary Lee
Brian Lucas
Dustin L. McMinn
Jessica Orf
Minqing Rong
Maria M. Toteva
Guifen Xu
Qiuping Ye
Wendy Zhong
Michael DeGraffenreid
Dineli Wickramasinghe
Jay P. Powers
Randall W. Hungate
Michael G. Johnson
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Citations (18)
Addressing PXR liabilities of phthalazine-based hedgehog/smoothened antagonists using novel pyridopyridazines
2010
Bioorganic & Medicinal Chemistry Letters
Jacob Kaizerman
Wade Aaron
Songzhu An
Richard J. Austin
Matthew Brown
Angela Chong
Tom Huang
Randall W. Hungate
Ben Jiang
Michael G. Johnson
Gary Lee
Brian Lucas
Jessica Orf
Minqing Rong
Maria M. Toteva
Dineli Wickramasinghe
Guifen Xu
Qiuping Ye
Wendy Zhong
Dustin L. McMinn
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Citations (23)
1