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Huiyu Zhou
Huiyu Zhou
Peking Union Medical College
HIV-1 protease
Chemistry
IC50
Protease
Biochemistry
3
Papers
13
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0
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Design and Evaluation of Novel Piperidine HIV-1 Protease Inhibitors with Potency against DRV-resistant Variants
2021
European Journal of Medicinal Chemistry
Mei Zhu
Huiyu Zhou
Ling Ma
Biao Dong
Jinming Zhou
Guoning Zhang
Minghua Wang
Juxian Wang
Shan Cen
Yucheng Wang
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Piperidine scaffold as the novel P2-ligands in cyclopropyl-containing HIV-1 protease inhibitors: Structure-based design, synthesis, biological evaluation and docking study.
2020
PLOS ONE
Huiyu Zhou
Mei Zhu
Ling Ma
Jinming Zhou
Biao Dong
Guoning Zhang
Shan Cen
Yucheng Wang
Juxian Wang
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Preliminary SAR and biological evaluation of potent HIV-1 protease inhibitors with pyrimidine bases as novel P2 ligands to enhance activity against DRV-resistant HIV-1 variants.
2019
European Journal of Medicinal Chemistry
Mei Zhu
Ling Ma
Huiyu Zhou
Biao Dong
Yujia Wang
Zhen Wang
Jinming Zhou
Guoning Zhang
Juxian Wang
Chen Liang
Shan Cen
Yucheng Wang
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Citations (12)
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