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Jean-Jacques Bourguignon

Centre national de la recherche scientifique
University of Strasbourg

194

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Synthesis, Antileishmanial Activity and in silico Studies of Aminoguanidine Hydrazones (AGH) and Thiosemicarbazones (TSC) Against Leishmania chagasi Amastigotes.

2021 Medicinal Chemistry
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Indole-3-guanylhydrazone hydrochloride mitigates long-term cognitive impairment in a neonatal sepsis model with involvement of MAPK and NFκB pathways

2020 Neurochemistry International
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Design and synthesis of 3-aminophthalazine derivatives and structural analogues as PDE5 inhibitors: anti-allodynic effect against neuropathic pain in a mouse model

2019 European Journal of Medicinal Chemistry
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Aminoguanidine Hydrazone Derivatives as Nonpeptide NPFF1 Receptor Antagonists Reverse Opioid Induced Hyperalgesia

2018 ACS Chemical Neuroscience
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Phenylpyridine-2-ylguanidines and rigid mimetics as novel inhibitors of TNFα overproduction: Beneficial action in models of neuropathic pain and of acute lung inflammation

2018 European Journal of Medicinal Chemistry
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RF313, an orally bioavailable neuropeptide FF receptor antagonist, opposes effects of RF-amide-related peptide-3 and opioid-induced hyperalgesia in rodents

2017 Neuropharmacology
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Development of a L‐Tryptophan‐Based Ligand for Regioselective Copper Catalyzed N2‐Arylation of 1,2,3‐Triazoles

2017
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Efficient and mild Ullmann-type N-arylation of amides, carbamates, and azoles in water.

2017 Chemistry: A European Journal
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Discovery of Imidazoquinazolinone Derivatives as TSPO Ligands Modulating Neurosteroidogenesis and Cellular Bioenergetics in Neuroblastoma Cells Expressing Amyloid Precursor Protein

2017
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Functionalization of 2H-1,2,3-Triazole C-Nucleoside Template via N2 Selective Arylation

2016 Journal of Organic Chemistry
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