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Hongfeng Yuan

City of Hope National Medical Center

10

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430

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SIRT1 activation by a c-MYC oncogenic network promotes the maintenance and drug resistance of human FLT3-ITD acute myeloid leukemia stem cells.

2014 Cell Stem Cell
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ATRA-induced cellular differentiation and CD38 expression inhibits acquisition of BCR-ABL mutations for CML acquired resistance.

2014 PLOS Genetics
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SIRT1 deacetylase promotes acquisition of genetic mutations for drug resistance in CML cells.

2013 Oncogene
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Activation of stress response gene SIRT1 by BCR-ABL promotes leukemogenesis

2012 Blood
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De Novo Acquisition of BCR-ABL Mutations for CML Acquired Resistance

2011
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BCR-ABL Gene Expression Is Required for Its Mutations in a Novel KCL-22 Cell Culture Model for Acquired Resistance of Chronic Myelogenous Leukemia

2010 Journal of Biological Chemistry
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BCR-ABL Gene Expression Is Required for Its Mutations in a Novel KCL-22 Cell Culture Model for Acquired Resistance of

2010
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Abstract B46: Essential roles of SIRT1 for BCR‐ABL transformation and genetic mutations

2009 Cancer Research
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Role of the SIRT1 Deacetylase in Survival and Imatinib Resistance of CML CD34+ Progenitors.

2009 Blood
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