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Doug J. Bartels

Vertex Pharmaceuticals

24

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1482

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Modeling population heterogeneity in viral dynamics for chronic hepatitis C infection: Insights from Phase 3 telaprevir clinical studies

2015 Journal of Pharmacokinetics and Pharmacodynamics
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Modeling Viral Evolutionary Dynamics after Telaprevir-Based Treatment

2014 PLOS Computational Biology
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Futility Rules for Telaprevir Combination Treatment for Patients With Hepatitis C Virus Infection

2013 Clinical Gastroenterology and Hepatology
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BRIEF COMMUNICATION Futility Rules for Telaprevir Combination Treatment for Patients With Hepatitis C Virus Infection

2013 Clinical Gastroenterology and Hepatology
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Modeling, Clinical and Virology Data From Phase 2 and 3 Studies Support 12-Week Telaprevir Duration in Combination With 24- or 48-Week Peginterferon/Ribavirin

2011 Gastroenterology
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Phenotypic Characterization of Resistant Val36 Variants of Hepatitis C Virus NS3-4A Serine Protease

2008 Antimicrobial Agents and Chemotherapy
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Natural Prevalence of Hepatitis C Virus Variants with Decreased Sensitivity to NS3·4A Protease Inhibitors in Treatment-Naive Subjects

2008 The Journal of Infectious Diseases
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[12] TELAPREVIR (VX-950) IS A POTENT INHIBITOR OF HCV NS3 PROTEASES DERIVED FROM GENOTYPE NON-1 HCV-INFECTED PATIENTS

2007 Journal of Hepatology
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Dynamic Hepatitis C Virus Genotypic and Phenotypic Changes in Patients Treated With the Protease Inhibitor Telaprevir

2007 Gastroenterology
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Phenotypic and structural analyses of hepatitis C virus NS3 protease Arg155 variants: sensitivity to telaprevir (VX-950) and interferon alpha.

2007 Journal of Biological Chemistry
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Citations (83)