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Justin D. Lutz

University of Washington

24

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Physiologically-Based Pharmacokinetic Modeling of Remdesivir and its Metabolites to Support Dose Selection for the Treatment of Pediatric Patients with COVID-19

2021 Clinical Pharmacology & Therapeutics
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Pharmacokinetic, Pharmacodynamic, and Drug-Interaction Profile of Remdesivir, a SARS-CoV-2 Replication Inhibitor.

2021 Clinical Pharmacokinectics
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Safety, pharmacokinetics and pharmacodynamics of selgantolimod, an oral Toll-like receptor 8 agonist: a Phase Ia study in healthy subjects.

2020 Antiviral Therapy
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Intestinal P-gp and Putative Hepatic OATP1B Induction: ITC Perspective on Drug Development Implications.

2020 Clinical Pharmacology & Therapeutics
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Cytochrome P450 3A Induction Predicts P‐glycoprotein Induction; Part 2: Prediction of Decreased Substrate Exposure After Rifabutin or Carbamazepine

2018 Clinical Pharmacology & Therapeutics
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Direct protein-protein interactions and substrate channeling between cellular retinoic acid binding proteins and CYP26B1.

2016 FEBS Letters
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Detection of an endogenous urinary biomarker associated with CYP2D6 activity using global metabolomics

2014 Pharmacogenomics
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A Specific Inhibitor of PfCDPK4 Blocks Malaria Transmission: Chemical-genetic Validation

2014 The Journal of Infectious Diseases
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Special Section on Prediction of Human Pharmacokinetic Parameters from In Vitro Systems Stereoselective Inhibition of CYP2C19 and CYP3A4 by Fluoxetine and Its Metabolite: Implications for Risk Assessment of Multiple Time- Dependent Inhibitor Systems s

2013
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Stereoselective Inhibition of CYP2C19 and CYP3A4 by Fluoxetine and its Metabolite: Implications For Risk Assessment of Multiple Time-dependent Inhibitor Systems

2013 Drug Metabolism and Disposition
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Citations (20)