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Yvonne Freund

Anacor Pharmaceuticals Inc.

53

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DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis

2021 Journal of Medicinal Chemistry
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In vivo efficacy of the boron-pleuromutilin AN11251 against Wolbachia of the rodent filarial nematode Litomosoides sigmodontis

2020 PLOS Neglected Tropical Diseases
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DNA methylation differences associated with peripheral biomarkers in the EMIF‐AD cohort.

2020 Alzheimers & Dementia
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Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs.

2020 PLOS Pathogens
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Plasmodium falciparum Resistance to a Lead Benzoxaborole Due to Blocked Compound Activation and Altered Ubiquitination or Sumoylation

2020 Mbio
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Identification of a potent benzoxaborole drug candidate for treating cryptosporidiosis.

2019 Nature Communications
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Boron-Pleuromutilins as Anti-Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis

2019 Journal of Medicinal Chemistry
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The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing

2018 PLOS Pathogens
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Identification of a 4-fluorobenzyl l-valinate amide benzoxaborole (AN11736) as a potential development candidate for the treatment of Animal African Trypanosomiasis (AAT)

2018 Bioorganic & Medicinal Chemistry Letters
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Host-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles

2018 PLOS Pathogens
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