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W. Lu
W. Lu
University of Oxford
Wnt signaling pathway
Notum
Cell biology
Chemistry
Enzyme
4
Papers
30
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Structural Insights into Notum Covalent Inhibition.
2021
Journal of Medicinal Chemistry
Yuguang Zhao
Fredrik Svensson
David Steadman
S. Frew
Amy Monaghan
Magda Bictash
Tiago Moreira
Rod Chalk
W. Lu
Paul V. Fish
E. Yvonne Jones
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Caffeine inhibits Notum activity by binding at the catalytic pocket.
2020
Yuguang Zhao
Jingshan Ren
James Hillier
W. Lu
E. Y. Jones
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Citations (7)
Structural characterisation of melatonin as an inhibitor of the Wnt deacylase Notum.
2020
Journal of Pineal Research
Yuguang Zhao
Jingshan Ren
James Hillier
Margaret Jones
W. Lu
E. Y. Jones
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The antiepileptic drug carbamazepine binds to a novel pocket on the Wnt receptor Frizzled-8
2020
Journal of Medicinal Chemistry
Yuguang Zhao
Jingshan Ren
J. Hillier
W. Lu
E. Y. Jones
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Citations (10)
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