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Charis Georgiou
Charis Georgiou
University of Edinburgh
Drug discovery
Chemistry
Gene isoform
Molecular biology
Biology
5
Papers
11
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Dynamic design: manipulation of millisecond timescale motions on the energy landscape of Cyclophilin A
2019
bioRxiv
Jordi Juárez-Jiménez
Arun A Gupta
Gogulan Karunanithy
Antonia S. J. S. Mey
Charis Georgiou
Harris Ioannidis
Alessio De Simone
Paul N. Barlow
Alison N. Hulme
Malcolm D. Walkinshaw
Andrew J. Baldwin
Julien Michel
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A computationally designed binding mode flip leads to a novel class of potent tri-vector cyclophilin inhibitors
2019
Chemical Science
A. De Simone
Charis Georgiou
Harris Ioannidis
A.A. Gupta
J.J. Jimenez
D.D. Shenton
Elizabeth A. Blackburn
Walkinshaw
Alison N. Hulme
Julien Michel
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Cyclophilin A complexed with the tri-vector ligand 8.
2018
Charis Georgiou
A. De Simone
Malcolm D. Walkinshaw
Julien Michel
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Pushing the Limits of Detection of Weak Binding Using Fragment-Based Drug Discovery: Identification of New Cyclophilin Binders.
2017
Journal of Molecular Biology
Charis Georgiou
Iain W. McNae
Martin A. Wear
Harris Ioannidis
Julien Michel
Malcolm D. Walkinshaw
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Citations (3)
1