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Junjun Chen

University of Delaware

10

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651

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A selective USP1–UAF1 inhibitor links deubiquitination to DNA damage responses

2014 Nature Chemical Biology
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Synthesis and Structure–Activity Relationship Studies of N-Benzyl-2-phenylpyrimidin-4-amine Derivatives as Potent USP1/UAF1 Deubiquitinase Inhibitors with Anticancer Activity against Nonsmall Cell Lung Cancer

2014 Journal of Medicinal Chemistry
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Serine Phosphorylation Is Critical for the Activation of Ubiquitin-Specific Protease 1 and Its Interaction with WD40-Repeat Protein UAF1

2012 Biochemistry
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A Noncanonical Cysteine Protease USP1 Is Activated through Active Site Modulation by USP1-Associated Factor 1

2012 Biochemistry
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The Handling of the Mechanistic Probe 5-Fluorouridine by the Pseudouridine Synthase TruA and Its Consistency with the Handling of the Same Probe by the Pseudouridine Synthases TruB and RluA †

2011 Biochemistry
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Ubiquitination of PCNA and Its Essential Role in Eukaryotic Translesion Synthesis

2011 Cell Biochemistry and Biophysics
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Chemically ubiquitylated PCNA as a probe for eukaryotic translesion DNA synthesis

2010 Nature Chemical Biology
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Crystal Structure of Pseudouridine Synthase RluA: Indirect Sequence Readout through Protein-Induced RNA Structure

2006 Molecular Cell
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Citations (69)