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Jacqueline M. Tremblay

Tufts University

41

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Identification and characterization of a new 34 kDa MORN motif-containing sporozoite surface-exposed protein, Cp-P34, unique to Cryptosporidium.

2021 International Journal for Parasitology
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A heterohexameric protein consisting of six linked single-domain antibodies is highly protective for BoNT/A, BoNT/B and BoNT/E exposures

2021 bioRxiv
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Camelid VHH Antibodies that Neutralize Botulinum Neurotoxin Serotype E Intoxication or Protease Function

2020 Toxins
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Structural Insights into Rational Design of Single-Domain Antibody-Based Antitoxins against Botulinum Neurotoxins

2020 Cell Reports
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Use of VHH antibodies for the development of antigen detection test for visceral leishmaniasis

2018 Parasite Immunology
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Singled-domain antibodies pinpoint potential targets within shigella invasion plasmid antigen D of the needle tip complex for inhibition of type III secretion

2017 Journal of Biological Chemistry
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A Tetraspecific VHH-based Neutralizing Antibody Modifies Disease Outcome in Three Animal Models of Clostridium difficile Infection

2016 Clinical and Vaccine Immunology
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Adenoviral Expression of a Bispecific VHH-Based Neutralizing Agent That Targets Protective Antigen Provides Prophylactic Protection from Anthrax in Mice

2016 Clinical and Vaccine Immunology
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A diverse set of single-domain antibodies (VHHs) against the anthrax toxin lethal and edema factors provides a basis for construction of a bispecific agent that protects against anthrax infection

2016 Journal of Biological Chemistry
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Adenovirus Vector Expressing Stx1/Stx2-Neutralizing Agent Protects Piglets Infected with Escherichia coli O157:H7 against Fatal Systemic Intoxication

2015 Infection and Immunity
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