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Naoko Niimi

Tokyo University of Pharmacy and Life Sciences

11

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183

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Catalytic and non‐catalytic roles of DNA polymerase κ in the protection of human cells against genotoxic stresses

2015 Environmental and Molecular Mutagenesis
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P-003 DNA polymerase kappa plays a role in in vivo translesion DNA synthesis over cisplatin adducts(Poster Sessions)

2015 Taikai Program Yoshisyu of the Environmental Mutagen Society of Japan
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P-075 An in vivo protective roles of DNA polymerase kappa against induction of DNA double strand breaks by mitomycin C : Immunohistological analysis with γ H2AX as an index(Poster Sessions)

2014 Taikai Program Yoshisyu of the Environmental Mutagen Society of Japan
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In vivo evidence that phenylalanine 171 acts as a molecular brake for translesion DNA synthesis across benzo[a]pyrene DNA adducts by human DNA polymerase κ

2014 DNA Repair
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DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation

2013 The EMBO Journal
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Phenylalanine 171 is a molecular brake for translesion synthesis across benzo[a]pyrene-guanine adducts by human DNA polymerase kappa.

2011 Mutation Research-genetic Toxicology and Environmental Mutagenesis
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R75: Caractérisation du rôle de l’ADN polymérase alternative kappa (Pol k) dans le checkpoint de la phase S

2010 Bulletin Du Cancer
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Critical amino acids in human DNA polymerases η and κ involved in erroneous incorporation of oxidized nucleotides

2010 Nucleic Acids Research
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The steric gate amino acid tyrosine 112 is required for efficient mismatched-primer extension by human DNA polymerase kappa.

2009 Biochemistry
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