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Mohammad Alzrigat

Science for Life Laboratory

8

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Targeting EZH2 in Multiple Myeloma—Multifaceted Anti-Tumor Activity

2018
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The miR-125a and miR-320c are potential tumor suppressor microRNAs epigenetically silenced by the polycomb repressive complex 2 in multiple myeloma

2017 RNA & DISEASE
- Mohammad Alzrigat
- Helena Jernberg-Wiklund
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Epigenetics in multiple myeloma: From mechanisms to therapy

2017 Seminars in Cancer Biology
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The polycomb group protein BMI-1 inhibitor PTC-209 is a potent anti-myeloma agent alone or in combination with epigenetic inhibitors targeting EZH2 and the BET bromodomains

2017 Oncotarget
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Genome-wide profiling of histone H3 lysine 27 and lysine 4 trimethylation in multiple myeloma reveals the importance of Polycomb gene targeting and highlights EZH2 as a potential therapeutic target.

2016 Oncotarget
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An Epigenomic Map of Multiple Myeloma Reveals the Importance of Polycomb Gene Silencing for the Malignancy

2014 Blood
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IKKα contains two conserved LXXLL co-activator motifs and is recruited to the retinoic acid receptor

2013
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